![]() ![]() For these advances to improve our understanding of human health, they must be deployed in well-phenotyped human samples and used to build resources such as variation catalogues 3, 4, control collections 5, 6 and imputation reference panels 7, 8, 9. Furthermore, combining TOPMed haplotypes with modern imputation methods improves the power and reach of genome-wide association studies to include variants down to a frequency of approximately 0.01%.Īdvancing DNA-sequencing technologies and decreasing costs are enabling researchers to explore human genetic variation at an unprecedented scale 2, 3. The extensive catalogue of genetic variation in TOPMed studies provides unique opportunities for exploring the contributions of rare and noncoding sequence variants to phenotypic variation. These rare variants provide insights into mutational processes and recent human evolutionary history. Among the more than 400 million detected variants, 97% have frequencies of less than 1% and 46% are singletons that are present in only one individual (53% among unrelated individuals). Additional previously undescribed variants were detected through assembly of unmapped reads and customized analysis in highly variable loci. ![]() In the first 53,831 TOPMed samples, we detected more than 400 million single-nucleotide and insertion or deletion variants after alignment with the reference genome. The resources include a variant browser, a genotype imputation server, and genomic and phenotypic data that are available through dbGaP (Database of Genotypes and Phenotypes) 1. Here we describe the TOPMed goals and design as well as the available resources and early insights obtained from the sequence data. The initial phases of the programme focused on whole-genome sequencing of individuals with rich phenotypic data and diverse backgrounds. The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of improving diagnosis, treatment and prevention of these diseases. Nature volume 590, pages 290–299 ( 2021) Cite this article NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium,.Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program ![]()
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![]() The recording itself is near real-time, but there is some noticeable lag between performing an action on your device and seeing the action occur in the QuickTime window. The QuickTime recording also recognizes iPhone or iPad rotation, so you’ll see the preview window on your Mac switch aspect ratios as you rotate your device. To provide that extra bit of professional polish, Apple automatically shows a clean iOS status bar, with full cellular reception, a full battery, and the historic 9:41 AM time setting, making your own iPhone recordings look just like Apple’s. Select your iPhone or iPad from the list and you’ll see your device’s screen replicated in the QuickTime window. This lets you select an alternate recording source, which now includes your iPhone or iPad. By default, QuickTime will activate your Mac’s built-in iSight camera, but ignore that and find and click on the small downward-facing triangle next to the record button. This will launch a new QuickTime window for video recording. Alternatively, you can use the keyboard shortcut Option-Command-N. Launch QuickTime and select File > New Movie Recording from the menu bar. ![]() Note that you may need to “ Trust” your Mac before the iPhone will work. Then connect your iPhone or iPad to your Mac using a Lightning cable. ![]() To record iPhone or iPad output on your Mac, make sure you’re running OS X Yosemite and iOS 8. With OS X Yosemite and iOS 8, Apple has now made recording the iPhone or iPad an easy and simple task. The ability to record an iPhone or iPad screen has long been available, but it required some work to get it going, such as jailbreak-only apps or AirPlay. ![]() ![]() The connexion is the little “tube” between the square elements. As for the input, click and drag on the recorder to add it on the main window and connect the “Recorders” to the inputs as presented in the gif.īe very careful that, as in the example, your recorders are connected to only one input. Now we need a recorder to record our audio. Use the same method to add as many inputs as you need for each mic you have. But if you use a more complex mic you should open the “Advanced” part on the menu to select which sources you exactly want. If you use the internal mic of your Mac, no more configuration to do. Click on the mic you just added to make the menu “Audio Source” appear. Now you have to configure your source to connect it to your mic. Pick the source “Input device”, click and drag it anywhere in the main window as in the gif below. To do that click open the source library (by clicking on “show library” if it’s closed). ![]() You will have a new window asking for the kind of Session you want to create, pick “New Blank Session”.įirst we’ll add the mics (1 in the figure). First open the software and go to Session > New Session (Cmd+N). We’ll get the voice of the other people through Skype to record it (4) and finally make us able to hear them (5).Īudio Hijack allows you to do all that almost as easily as the figure. All these voices will be sent in Skype (3) so that the other podcast member online we hear us. We’ll have one or several mics (1) that we will record in different files (2). We’ll use Audio Hijack and our objective is to create a configuration similar to the one below.
![]() ![]() The ground hyperfine levels a and b of 87Rb have angular momenta F a=1 and F b=2, and the upper and lower clock states are written as |+〉≡| b, m=0〉 and |−〉≡| a, m=0〉, respectively. ![]() We thereby take advantage of the magnetic insensitivity of the so-called clock transition, the energy of which depends only quadratically on the magnetic field strength. Here, we report achieving this goal by confining rubidium-87 atoms in an optical lattice of 25 μm period using the ground-state atomic hyperfine transition for storage. To demonstrate quantum memory lifetimes of many milliseconds, we must suppress atomic motion and use magnetically insensitive atomic coherence as the basis of the quantum memory. ![]() Millisecond storage of classical, coherent light has been reported in atomic gases 24, 25, 26, whereas coherence times in excess of 1 s have been achieved in the solid state 27. Ballistic expansion of the freely falling gas provides a longer memory time limitation, which can be estimated from the time τ= Λ/(2π v) ∼100 μs it takes an atomic spin grating to dephase by atomic motion (we use some representative parameters typical of the magneto-optical trap (MOT) environment: grating wavelength Λ=50 μm, atomic velocity for T=70 μK and rubidium mass M). In short, equally populated atomic states of opposite magnetization, ± m μ B, where m is the angular momentum projection and μ B is the Bohr magneton, respond asymmetrically to ambient fields 16, 17, 18, 19, 20, 21, 22, 23. The rubidium sample, prepared in a state of zero average magnetization, was allowed to freely fall during the protocol and the quantum memory time was limited by the effects of small uncompensated magnetic fields. The longest quantum memory time previously reported, 32 μs in a cold rubidium ensemble 6, is insufficient to carry out quantum repeater protocols over the distances where direct transmission fails. Such long-lived quantum memories could revolutionize deterministic single-photon sources 6 and lead to the generation of entangled states over extended systems 13.Įnhancing the matter coupling to a single spatial light mode is an advantage shared by cold optically thick atomic ensembles 14 and single atoms in high-finesse cavities 15. For L ∼1,000 km, required memory times vary from many seconds for a simple network topology 8, 9 to milliseconds for more complex (for example, multiplexed) topologies and architectures 10, 11, 12. The entanglement distribution rate of a network depends critically on the memory time of these storage elements. Entanglement distributed over these shorter links is then connected over length L according to a family of protocols generically known as the quantum repeater 8. The division circumvents attenuation in the fibre provided the intermediate memory nodes, which terminate the links, have a non-zero quantum memory time. To distribute entanglement over longer distances, the channel should be divided into links of length ≤ l. In practice, direct entanglement distribution over optical fibres is limited by absorption to distances l ∼100 km. For L=1,000 km, L/ c≈5 ms for an optical fibre. ![]() For the distribution of entanglement over a length L, the characteristic timescale for storage is the light travel time L/ c, where c is the speed of light in the medium. The generation of such remote entanglement must necessarily be done locally and distributed by light transmission over optical fibre links or through free space 7. Protocols for quantum communication are typically based on remote parties sharing and storing an entangled quantum state. ![]() ![]() ![]() How Adobe defines its PDF reader Adobe Acrobat Reader DC. PhotoSweeper also serves as an up-to-date photo browser with a built-in search of photos by metadata, Quick Look preview, the "Info" panel with a detailed photo description, including histogram and image metadata (EXIF, IPTC etc.). Adobe Acrobat Reader is a free PDF reader that has set itself as the standard software to open PDF documents.Amongst its many features this PDF reader includes printing, adding comments, e-signing your PDF documents and sync features with multiple devices. PhotoSweeper provides 3 modes for reviewing results: “One by One”, ”Face-to-Face" - one or two large photos with an opportunity to mark a photo with just a click, “All in One“ - all groups of duplicates in one list. Mark photos you want to get rid of manually, or use the "Auto Mark" feature to mark duplicates automatically based on the list of rules you can adjust to your needs in the Preferences. Using caches makes the next comparison much faster. You can regroup the results without re-comparing photos by changing matching level with a slider. Cutting-edge technologies and unique algorithms make searching duplicates incredibly fast and gives excellent comparison results. PhotoSweeper was developed as a tool for extremely fast comparison of a huge number of photos. It allow you to compare the contents of two folders with each other or find similar photos to a single image. The app finds duplicate photos, even those edited in external programs such Photoshop, regardless of image size or format.įind duplicates between two groups of photos while ignoring those inside each group. Powerful multi-settings to easily find duplicates, similar photos, series of shots. It works with Photos, iPhoto, Aperture, Capture One, and Lightroom media libraries as well as photos from your hard drives and external storage. Add more photos from your Photos, Capture One or Lightroom Classic library via the Media Browser window. It is a fast, precise & super efficient tool to eliminate similar or duplicate photos even in huge photo collections. If for whatever reason you’re keeping all your photos on a Mac, PhotoSweeper is an excellent alternative. Just drag and drop folders from your Mac to allow PhotoSweeper to find all photos inside. Unfortunately, AllDup is only available for Windows. You have a mess in your photo collection or just want to free disk space by removing junk photos.You have photos scattered on external hard drives and local disks, in Apple Photos, Lightroom Classic or Capture One libraries.You edit photos with software like Photoshop, Pixelmator etc., and make backups just in case. ![]() You take a series of shots of the same scene trying to get the perfect one."I do like this app, it works really well and under the hood is written to utilize the abilities of your Mac." MacTricksAndTips Optimized for Apple silicon Buy Now 9. "PhotoSweeper is a simple and efficient utility for organizing photos. PhotoSweeper is a swift and powerful duplicate photos cleaner built to help you find and delete duplicate and similar photos on your Mac. This free PC software is developed for Windows XP/Vista/7/8/10/11 environment, 32-bit version. The following version: 1.4 is the most frequently downloaded one by the program users. "PhotoSweeper packs a powerful punch in de-cluttering any size collection. Commonly, this programs installer has the following filename:. “Swift, easy to use, thorough, analyzes specific libraries, can search according to various criteria, offers choices in photo handling” TheNextWeb It works with Photos, iPhoto, Aperture, Capture One and Lightroom Classic media libraries as well as photos from your hard drives and external storages. holds the license to use the name and logo of Filehippo".PhotoSweeper is a fast, precise & super efficient tool to eliminate similar or duplicate photos even in huge photo collections. Softonic later acquired FileHippo as of 2022 the FileHippo home page states "Softonic International, S.A. FileHippo does not accept software submissions from publishers. FileHippo was estimated to be worth over US$13,000,000 in November 2015. įileHippo was established in 2004 by the UK-based technology company Well Known Media. Before the acquisition by Softonic the FileHippo website, funded by user donations and third-party advertising, had an Update Checker, later renamed App Manager, a free program that scanned a computer for outdated software and offered links to more recent versions. PhotoSweeper is a fast, precise & super efficient tool to eliminate similar or duplicate photos even in huge photo collections. Registration is not required in this website. The website has sections listing most recently updated programs and most popular downloads, organised by category, with program information and link. English, German, Spanish, French, Italian, Polish, Japanese, ChineseįileHippo is a software downloading website that offers computer software for Windows. ![]() ![]() He had never seen an inkling of such creatures, and presumed they were too afraid of the Count’s diabolical ways to stray into the courtyard, much less fly through an open window.Īnd so, casting that rumination from him, he walked, and surveyed. Would he be left for the wolves, or would his bones be left in some dreadful location in these halls?ĭoubtless, not even the crows or other carrion birds would be able to locate his remains. No, he knew not the hour, as he had thought, nor the method, nor what was to be left of him, if anything. The final letter had been noted as the 29th instant, so he had but five more days. He had held the letter he was induced to write, and then dated it for the Count. In other moments, he found himself slipping into an odd serenity an acceptance of his fate that was, perhaps, dangerous to allow to continue.įor unlike other men, he knew the date, if not the hour, of the day he was to die. He rubbed his arms, both to soothe himself, as well as to ward off a slight chill.Īs Jonathan wandered the corridors, he was by turns anxious at the potential reappearance of his client his captor his gaoler his formerly presumed beneficiary in a splendid deal that may have left him quite well off for his future life. He knew it wasn’t safe to loiter, and pulled his thin jacket tighter about himself. Or perhaps he ought to call them what they were battlements of a bygone age. It was a balmy night within the castle, save for when the wind picked up. He was, by turns, pondering what it once had been in bygone days, in accordance with the Count’s speeches. ![]() ![]() ![]() It was the night of June 24th, as Jonathan Harker did his level best to find a way that would lead him out of this accursed place, and from this accursed land. ![]() ![]()
![]() ![]() Eas圜atalog integrates with your existing data source, no new database is required. Eas圜atalog can group common records together and paginate them into the same library item automatically. ![]() Sometimes, groups of records need to appear together on the page - perhaps in a table. For example, if your catalog is output in a section > sub-section format, each product would need to know which section in the catalog it belongs to. If you re producing a structured document, additional information regarding the structure needs to be available in the data. Similarly, each field must have a unique name. Typically this would be an SKU or product code and is required so that we can always find the correct record when updating the document. Each record must have a unique identifier that never changes for the life of the product. These can be in the form of full paths, partial paths or Eas圜atalog can also download images from URLs in the source data. References to image files that you need to paginate. Often, customers have partial or incomplete data: before you begin, ensure that you have: Everything that you need to appear on the printed page needs to be available in the source data. Eas圜atalog is very data driven, so the quality of the source data has a direct impact on both the quality of the final output and the return on investment you ll see from using Eas圜atalog. Updates, edits, checking for errorsĢ Good quality source data is the key to successful catalog automation with Eas圜atalog. Beginning the task of automating your catalog production using Eas圜atalog can sometimes seem like a daunting process, but this white paper gives an overview of how to best prepare to ensure a successful implementation. Your marketing material can be assembled automatically at the click of a button, resulting in significant time and cost savings. All of your content can be published directly from your database or spreadsheet into Adobe InDesign and can be kept right up-to-date. Whether your data is stored in an ODBC database such as MySQL, a PIM system, Asset Management systems such as Elvis or even a spreadsheet Eas圜atalog can help by automating your catalog production. Often, though, this data is not repurposed for the printed page. With the advent of the Internet, many companies invested in databases for their online stores. In the case of multi-language versions, this process can be repeated multiple times. If there's a last minute price-update, hundreds of pages may need to be updated resulting in the edit, proof-read process starting over again. ![]() In turn, this leads to an extended proofreading stage at the end of production to ensure that the document is both accurate and free from errors. Designers are required to manually enter data onto the page, significantly increasing production time all while trying to ensure that no errors occur. Design projects on all types of data sources, single or multiple.1 INTRODUCTION Producing catalogs, brochures, price lists and marketing material can be a costly and time-consuming process.Degressive tariffs starting from 5 licenses.Recognized by thousands of users in more than 30 countries on six continents, Eas圜atalog has quickly established itself as one of the most powerful and flexible automatic layout solutions.Īssociated with our platform, Eas圜atalog makes it possible to automatically generate the pages of the briefs, or railroads, of the publications made in PimCore.Īutomatic placement of products in pages, including sizes and positions, with real-time updates.Īctive Publishing, official partner and reseller of the Eas圜atalog plugin for InDesign, offers you: Ideal for multilingual publications, Eas圜atalog dramatically reduces page production time and ensures your documents remain error-free. ) or databases, generate your pages and update them at your convenience in a few clicks Connect Adobe® InDesign® to different data sources, files (xml, Excel. ![]() ![]() Unless you are looking for help with fan project related to Undertale, please don't make posts that are just invitation to subreddit or discord.Do not ask users to participate in anything that is not Undertale-based.As such do not discuss or share screenshots of these versions here. Additionally, since there is no official port of Undertale to mobile devices, most of the available ones count as piracy too. Discussions of piracy and attempts of illegal distribution of the game are not allowed.Don't promote the kinds of merchandise that Toby is not okay with.Do not share or discuss content that is more sexually suggestive or obscene than the game itself.ģ) No bootleg merchandise and pirated content.If the connection to UT/DR is too tenuous, the post may be removed under this rule as well.Ģ) No sexual or otherwise obscene content Keep your posts on topic! Posts discussing/sharing content about Undertale AUs, Deltarune AUs, or the subreddit itself are also permitted.Breakdown of purpose and use of subreddit’s flairs.Please look here before submitting Question posts. Frequently asked questions about playing the game and fandom at large.Pinned mini-event posts focusing on various corners of UT community.Ban appeal form for it can be found here. ![]()
![]() From fitment help from our in-house wheel experts to shipping packages, we'll take care of you and your order every step of the way. Regardless of what styles or sizes you're interested in, the one thing you can depend on to come up with every product order is the best buying experience in the business. Why You Should Purchase DiabloSport at Vivid Racing They are an industry leader in vehicle calibration, which is performed by ?flashing? or re-programming vehicles through the OBD-II port (Diagnostics port). DiabloSport is a manufacturer of high-performance automotive electronics that re-program a vehicle?s factory computer. DiabloSport will not settle for anything but the maximum horsepower and torque gains over stock. They use an in-ground SuperFlow Chassis dyno to make and develop their performance tunes, and then they take the cars out on the Florida streets to see what they have. ![]() Their goal is to continue offering innovative electronics that are loaded with industry-leading ?tune? files that create better power, economy, and drivability on late model cars and trucks Quality and Performance You Can TrustĭiabloSport is made up of a team of people who are horsepower junkies by trade- making the biggest possible power gain is why they go to work every day. Today, they are the only company to offer color touch screen hand-held programmers in all of their OBD-II flash devices. Since 2001, DiabloSport offers industry-leading performance programmers that stay ahead of the technology curves. Whether gas or diesel powered, our products optimize a vehicle?s performance by programming its factory computer or plugging it into its factory engine harness. They focus on making the maximum power, drivability, and fuel economy gain on late model fuel injected vehicles. It is as simple as it sounds.DiabloSport is an industry-leading manufacturer of automotive performance programmers based in Sanford, Florida. Just plug into your OBD II port and drive. No need to pay hefty money to your mechanic for installation. Changing tire size, gears, shifting or reading and clearing DTC codes have never been so easy. GM/Chevy Duramax: Up to 135 HP & 240 TQ Top Features High-Resolution Full Color Screenĭiablosport Predator 2 houses a High-Resolution Color Screen in a slim and sleek case which fits true to the saying "Big things come in small packages".ĭiablosport Predator includes 5 buttons in order to provide a smooth navigation over your screen.
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